Thiotepa Impurity 3 Sodium Salt CAS 14056-57-6 (free acid)

Description

The occurrence of Thiotepa Impurity 3 Sodium Salt is closely related to an amide group, sulfur-containing functionality, organophosphorus functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Thiotepa Impurity 3 Sodium Salt (CAS 14056-57-6 (free acid)) is a certified pharmaceutical impurity reference standard with the molecular formula C4H8N2OPSNa and a molecular weight of 186.15 g/mol.

Owing to an amide group, sulfur-containing functionality, organophosphorus functionality, a hydroxyl group, an ether linkage, Thiotepa Impurity 3 Sodium Salt is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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